Tesamorelin 10mg

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Tesamorelin Peptide (RUO) | High Purity ≥99% | Research Grade

Product Specifications

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What Is Tesamorelin?

Tesamorelin is a 44-amino acid synthetic analog of endogenous human Growth Hormone-Releasing Hormone (GHRH) and is supplied exclusively for laboratory and preclinical research applications. Structurally homologous to the full-length N-terminal fragment of human GHRH, Tesamorelin is distinguished by a specific N-terminal modification: the addition of a trans-3-hexenoyl group investigated in research literature for its steric shielding properties and potential resistance to enzymatic cleavage by dipeptidyl peptidase-4 (DPP-4).

Unlike the truncated 29-amino acid GHRH analogs (Modified GRF 1-29, Sermorelin), Tesamorelin retains the complete 44-amino acid GHRH sequence with this N-terminal fatty acid modification — a structural distinction that is a primary subject of peptide stability and pharmacodynamic research comparing full-length versus truncated GHRH scaffold performance in experimental models.

Tesamorelin is widely referenced in metabolic, neuroendocrine, and hepatic research literature for its characterized activity at GHRH receptors on anterior pituitary somatotrophs and its documented role in pulsatile GH release and IGF-1 axis modulation in preclinical and clinical research models.

Manufactured under controlled conditions and supplied in lyophilized form, Tesamorelin is commonly utilized by qualified researchers requiring high-purity, batch-consistent materials for controlled experimental studies.

This product is clearly labeled and distributed strictly as a Research Use Only (RUO) material and is not approved for human or veterinary use.

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Experimental Research Applications

In scientific literature, Tesamorelin has been investigated in a variety of experimental settings, including:

• GHRH receptor binding and somatotroph activation research
• Pulsatile GH release and GH-IGF-1 axis modulation studies
• Visceral adipose tissue biology and lipolytic pathway research (LPL, HSL)
• Hepatic steatosis models and mitochondrial oxidation pathway studies
• De novo lipogenesis pathway investigations in hepatic models
• DPP-4 enzymatic resistance and peptide stability research
• N-terminal fatty acid modification and pharmacodynamic studies
• Peripheral nerve regeneration and axonal outgrowth models
• Comparative full-length vs. truncated GHRH analog scaffold research

These studies are conducted exclusively within laboratory and preclinical environments and are intended for mechanistic and observational research purposes.

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Purity and Quality Control

Each batch of Tesamorelin undergoes analytical testing to ensure:

✔ ≥99% purity verified by HPLC

✔ LC-MS molecular weight (~5,135.9 Da) and sequence identity confirmed per batch

✔ Batch-to-batch consistency

✔ Professional documentation and traceability

✔ Controlled manufacturing standards

✔ Reliable performance for repeatable research applications

High analytical purity and strict quality control procedures help provide researchers with confidence in the consistency and reliability of each batch.

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Key Research Features

• Full-length 44-amino acid GHRH analog
• N-terminal trans-3-hexenoyl modification — DPP-4 resistance research tool
• Pulsatile GH release profile in preclinical research models
• Characterized in metabolic, hepatic, and neuroendocrine research literature
• ≥99% HPLC-verified purity
• LC-MS sequence and molecular weight identity confirmed
• Lyophilized powder format
• Hygroscopic — allow to reach room temperature before opening
• Suitable for in vitro and preclinical research
• Batch-tested for consistency
• Research-grade manufacturing standards
• Professionally labeled and documented

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Storage Recommendations

To maintain product stability and research integrity, Tesamorelin should be:

• Stored at −20°C in a tightly sealed container
• Protected from light and moisture
• Allowed to reach room temperature before opening to prevent moisture absorption (hygroscopic)
• Reconstituted with aqueous laboratory-grade solvent according to standard peptide laboratory protocols
• Kept sealed until use
• Handled according to standard laboratory procedures

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Toxicology and Regulatory Information

• Evaluated in preclinical and clinical metabolic, hepatic, and neuroendocrine research models
• FDA-approved as Egrifta (tesamorelin for injection) for a specific HIV-associated lipodystrophy indication — this RUO research reagent is distinct from any approved pharmaceutical product and is not supplied for therapeutic use
• Supplied strictly as a Research Use Only (RUO) material
• Not a dietary supplement, nutraceutical, or consumer product

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Why Choose Summit Pep Labs?

At Summit Pep Labs, we are committed to supplying researchers with premium-quality compounds manufactured to rigorous analytical standards.

Why Researchers Choose Summit Pep Labs

• ≥99% HPLC-verified purity
• LC-MS sequence and molecular weight identity confirmed per batch
• Batch consistency and traceability
• Professional labeling and packaging
• Research-grade manufacturing standards
• Secure shipping and quality assurance
• Commitment to reproducibility and reliability

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Frequently Asked Questions

What is Tesamorelin?
Tesamorelin is a 44-amino acid synthetic GHRH analog with an N-terminal trans-3-hexenoyl modification, commonly referenced in scientific literature for GHRH receptor signaling, pulsatile GH axis research, visceral adipose tissue biology, hepatic steatosis models, and DPP-4 enzymatic resistance studies in laboratory and preclinical environments.

How does Tesamorelin differ from CJC-1295 Without DAC or Sermorelin?
Tesamorelin retains the complete 44-amino acid GHRH sequence — the same length as native GHRH — with an N-terminal trans-3-hexenoyl fatty acid modification. CJC-1295 Without DAC and Sermorelin are both truncated 29-amino acid GHRH fragments. This full-length sequence with fatty acid modification makes Tesamorelin a distinct research scaffold for comparing full-length versus truncated GHRH analog pharmacodynamics.

Is Tesamorelin approved for human use?
Tesamorelin is FDA-approved as a pharmaceutical product (Egrifta) for a specific HIV-associated lipodystrophy indication. This product is a research reagent supplied strictly as a Research Use Only (RUO) material and is entirely distinct from any approved pharmaceutical product. It is not approved, labeled, or supplied for human or veterinary use.

What purity does Summit Pep Labs provide?
Each batch of Tesamorelin is tested and verified to contain ≥99% purity using HPLC analytical methods, with LC-MS molecular weight and sequence identity confirmation per batch.

How is Tesamorelin supplied?
Tesamorelin is supplied as a lyophilized powder and packaged according to professional research standards.

How should Tesamorelin be stored?
Store at −20°C, protected from light and moisture. This material is hygroscopic — allow vials to reach room temperature before opening to prevent moisture absorption. Reconstitute with aqueous laboratory-grade solvent according to standard peptide laboratory protocols.

Is a Certificate of Analysis available?
Yes. A batch-specific Certificate of Analysis documenting HPLC purity (≥99%) and LC-MS identity confirmation is available per batch.

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References

• Grinspoon S et al. Metabolic effects of a growth hormone-releasing factor. N Engl J Med. 2007
• Stanley TL et al. Effects of tesamorelin on non-alcoholic fatty liver disease in HIV. Lancet HIV. 2019
• Falutz J et al. Effects of tesamorelin — pooled analysis of two phase 3 trials. J Clin Endocrinol Metab. 2010
• Russo M et al. Efficacy and safety of tesamorelin in people with HIV on integrase inhibitors. AIDS. 2024
• PubChem Compound Summary — Tesamorelin
• National Center for Biotechnology Information (NCBI)
• U.S. Food and Drug Administration (FDA)

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Research Use Only Disclaimer

For Research Use Only (RUO).

This product is intended strictly for laboratory and scientific research purposes. It is not intended for human consumption, veterinary use, cosmetic applications, therapeutic use, or diagnostic purposes.

By purchasing this product, customers acknowledge that they are qualified researchers and agree to use these materials in accordance with all applicable laws and regulations.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.