GHK-Cu (Copper Tripeptide-1) (RUO) | High Purity ≥99% | Research Grade
Product Specifications
| Specification | Details |
|---|---|
| Product Name | GHK-Cu (Copper Tripeptide-1) |
| Peptide Type | Copper-Complexed Tripeptide (3 Amino Acids) |
| CAS Number | 89030-95-5 |
| Molecular Formula | C₁₄H₂₃CuN₆O₄ |
| Molecular Weight | 340.4 Da |
| Purity | ≥99% (RP-HPLC Verified) |
| Identity Confirmation | LC-MS Verified |
| Endotoxin | <0.25 EU (LAL Assay) |
| Form | Lyophilized Powder |
| Solubility | Water Soluble (pH 4–6 buffer recommended) |
| Storage | 2–8°C lyophilized; −20°C in solution. Protected from light and moisture. |
What Is GHK-Cu?
GHK-Cu (Copper Tripeptide-1) is a naturally occurring copper-complexed tripeptide first isolated from human plasma albumin and is supplied exclusively for laboratory and preclinical research applications. Identified by CAS Number 89030-95-5, GHK-Cu is widely referenced in peptide research literature due to its characterized copper coordination chemistry, defined molecular structure, and reproducible analytical profile.
Manufactured under controlled conditions and supplied in lyophilized form, GHK-Cu is commonly utilized by qualified researchers requiring high-purity, batch-consistent materials for controlled experimental studies.
This product is clearly labeled and distributed strictly as a Research Use Only (RUO) material and is not approved for human or veterinary use.
Experimental Research Applications
In scientific literature, GHK-Cu has been investigated in a variety of experimental settings, including:
- Extracellular matrix (ECM) remodeling and collagen synthesis research
- MMP/TIMP protease balance studies
- NF-κB and MAPK inflammatory pathway investigations
- SIRT1 and STAT3 signaling research
- Copper coordination and redox chemistry studies
- Biomaterials and peptide delivery system research
- Cellular and tissue-level investigations
These studies are conducted exclusively within laboratory and preclinical environments and are intended for mechanistic and observational research purposes.
Purity and Quality Control
Each batch of GHK-Cu undergoes analytical testing to ensure:
✔ ≥99% purity verified by RP-HPLC
✔ LC-MS identity and molecular weight confirmation
✔ Cu:peptide stoichiometric ratio verification
✔ Endotoxin screening <0.25 EU (LAL assay)
✔ Batch-to-batch consistency
✔ Professional documentation and traceability
✔ Controlled manufacturing standards
✔ Reliable performance for repeatable research applications
High analytical purity and strict quality control procedures help provide researchers with confidence in the consistency and reliability of each batch.
Key Research Features
- Copper-complexed tripeptide (Gly-His-Lys + Cu²⁺)
- ≥99% RP-HPLC-verified purity
- LC-MS identity confirmed
- Cu:peptide stoichiometry verified
- Endotoxin screened (<0.25 EU)
- Lyophilized powder format
- Water soluble
- Suitable for in vitro and preclinical research
- Batch-tested for consistency
- Research-grade manufacturing standards
- Professionally labeled and documented
Storage Recommendations
To maintain product stability and research integrity, GHK-Cu should be:
- Stored at 2–8°C (lyophilized) or −20°C (in solution)
- Reconstituted in aqueous buffer at pH 4–6 for optimal complex stability
- Protected from light and moisture
- Kept sealed until use
- Handled according to standard laboratory procedures
Toxicology and Regulatory Information
- Evaluated in preclinical toxicology and biomaterials research models
- No FDA-approved GHK-Cu drug product exists
- Supplied strictly as a Research Use Only (RUO) material
- Cosmetic ingredient status only (INCI: Copper Tripeptide-1) for finished cosmetic products
Why Choose Summit Pep Labs?
At Summit Pep Labs, we are committed to supplying researchers with premium-quality compounds manufactured to rigorous analytical standards.
Why Researchers Choose Summit Pep Labs
- ≥99% HPLC-verified purity
- Cu:peptide stoichiometry verified — not just peptide purity
- LC-MS identity confirmation
- Batch consistency and traceability
- Professional labeling and packaging
- Research-grade manufacturing standards
- Secure shipping and quality assurance
- Commitment to reproducibility and reliability
Frequently Asked Questions
What is GHK-Cu?
GHK-Cu is a naturally occurring copper-complexed tripeptide (Glycyl-L-Histidyl-L-Lysine + Cu²⁺) commonly referenced in scientific literature for laboratory and preclinical research applications.
Is GHK-Cu approved for human use?
No. GHK-Cu is not approved by the FDA for human or veterinary use. It is supplied exclusively for research purposes.
What purity does Summit Pep Labs provide?
Each batch of GHK-Cu is tested and verified to contain ≥99% purity by RP-HPLC, with LC-MS identity confirmation and Cu:peptide stoichiometric ratio verification.
How is GHK-Cu supplied?
GHK-Cu is supplied as a lyophilized powder and packaged according to professional research standards.
How should GHK-Cu be stored?
For optimal stability and research integrity, lyophilized GHK-Cu should be stored at 2–8°C and protected from light and moisture. Once reconstituted, store at −20°C in single-use aliquots. Aqueous buffer at pH 4–6 is recommended for reconstitution to maintain complex stability.
What is the difference between GHK and GHK-Cu?
GHK is the apo-tripeptide without copper coordination. GHK-Cu is the copper-complexed form where Cu²⁺ is coordinated by the imidazole nitrogen of histidine, the alpha-amino group of glycine, and the deprotonated amide nitrogen. The complexed form exhibits distinct redox reactivity not present in the apo-peptide, making it the required form for copper-mediated pathway research.
References
- Pickart L, Margolina A. Int J Mol Sci 2018 (PMC6073405)
- Maquart FX et al. FEBS Letters 1988;238:343
- Pickart L et al. Oxid Med Cell Longev 2012 (PMC3359723)
- Bertini I et al. Inorg Chem 2021 (PMC8653159)
- PubChem Compound Summary – GHK-Cu (CID 378611)
- National Center for Biotechnology Information (NCBI)
- U.S. Food and Drug Administration (FDA)
- CIR Safety Assessment – Copper Tripeptide-1
Research Use Only Disclaimer
For Research Use Only (RUO).
This product is intended strictly for laboratory and scientific research purposes. It is not intended for human consumption, veterinary use, cosmetic applications, therapeutic use, or diagnostic purposes.
By purchasing this product, customers acknowledge that they are qualified researchers and agree to use these materials in accordance with all applicable laws and regulations.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Josh Owens (verified owner) –
great quality product. Already see results